Dentin-Pulp Complex Regeneration Therapy Following Pulp Amputation
نویسندگان
چکیده
Dental pulp, which is surrounded by hard tissue (dentin and enamel), consists of pulp cells, odontoblasts, endothelial cells, neurons, immune system cells, and the extracellular matrix, and plays key roles in maintaining the function of healthy teeth [1]. Via the apical foramen of tooth, blood vessels supply nutrients to the tooth and remove waste products, and neural network warns for harmful stimuli as pain [2]. Immune system cells including dendritic cells, macrophages, and T-lymphocytes, prevent entry of microorganisms and other foreign antigens [2]. Pulp cells and odontoblasts repair dentin that has been lost due to tooth wear or dental caries, by depositing tertiary dentin on the pulp chamber surface as a protective physical barrier in order to block exogenous stimuli [2].
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